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Natural diterpenes from coffee, cafestol and kahweol induce apoptosis through regulation of specificity protein 1 expression in human malignant pleural mesothelioma

BACKGROUND: Malignant pleural mesothelioma (MPM) is a highly aggressive cancer with a very poor prognosis. Several clinical studies such as immunotherapy, gene therapy and molecular targeting agents have been tried for treatment of malignant mesothelioma, however, there is no application for effecti...

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Hlavní autoři: Lee, Kyung-Ae, Chae, Jung-Il, Shim, Jung-Hyun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431247/
https://ncbi.nlm.nih.gov/pubmed/22734486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-60
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