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Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3(2)

BACKGROUND: Systems biology approaches to study metabolic switching in Streptomyces coelicolor A3(2) depend on cultivation conditions ensuring high reproducibility and distinct phases of culture growth and secondary metabolite production. In addition, biomass concentrations must be sufficiently high...

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Detalhes bibliográficos
Main Authors: Wentzel, Alexander, Bruheim, Per, Øverby, Anders, Jakobsen, Øyvind M, Sletta, Håvard, Omara, Walid A M, Hodgson, David A, Ellingsen, Trond E
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431225/
https://ncbi.nlm.nih.gov/pubmed/22676814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-59
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