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Studies on the biological role of DNA methylation. II. Role of phiX174 DNA methylation in the process of viral progeny DNA synthesis.

In vivo inhibition of bacteriophage phiX174 DNA methylation by nicotinamide resulted in the accumulation of replicative intermediates with multiple-genome length single-stranded "tails". These abnormal replicative intermediates could not be chased into viral single-stranded circular DNA. The effect...

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Pubblicato in:Nucleic Acids Res
Autori principali: Friedman, J, Razin, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1976
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343120/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/136644/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/3.10.2665
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