Efficient Hepatitis C Virus Particle Formation Requires Diacylglycerol Acyltransferase 1 (DGAT1)

Hepatitis C virus (HCV) infection is closely tied to the lipid metabolism of liver cells. Here, we identify the triglyceride-synthesizing enzyme DGAT1 as an important host factor for HCV infection; DGAT1 interacts with the viral nucleocapsid core and is required for the trafficking of core to lipid...

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Main Authors: Herker, Eva, Harris, Charles, Hernandez, Céline, Carpentier, Arnaud, Kaehlcke, Katrin, Rosenberg, Arielle R., Farese, Robert V., Ott, Melanie
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431199/
https://ncbi.nlm.nih.gov/pubmed/20935628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2238
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