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Radical Acceleration of Nuclear Reprogramming by Chromatin Remodeling with the Transactivation Domain of MyoD

Induced pluripotent stem cells (iPSCs) can be created by reprogramming differentiated cells through introduction of defined genes, most commonly Oct4, Sox2, Klf4, and c-Myc (OSKM). However, this process is slow and extremely inefficient. Here, we demonstrate radical acceleration of iPSC creation wit...

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Bibliographische Detailangaben
Hauptverfasser: Hirai, Hiroyuki, Tani, Tetsuya, Katoku-Kikyo, Nobuko, Kellner, Steven, Karian, Peter, Firpo, Meri, Kikyo, Nobuaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431196/
https://ncbi.nlm.nih.gov/pubmed/21732495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.684
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