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PPARγ Ligands Regulate Noncontractile and Contractile Functions of Airway Smooth Muscle: Implications for Asthma Therapy

In asthma, the increase in airway smooth muscle (ASM) can contribute to inflammation, airway wall remodeling and airway hyperresponsiveness (AHR). Targetting peroxisome proliferator-activated receptor γ (PPARγ), a receptor upregulated in ASM in asthmatic airways, may provide a novel approach to regu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Donovan, Chantal, Tan, Xiahui, Bourke, Jane Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431171/
https://ncbi.nlm.nih.gov/pubmed/22966222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/809164
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