Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters

Resistance and relapse are still primary causes that result in poor effectiveness of chemotherapy in malignant gliomas. Therefore, development of new therapeutic strategies requires the identification of key molecular pathways regulating chemoresistance. We previously found that abnormal high expres...

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Main Authors: Martin, V, Xu, J, Pabbisetty, SK, Alonso, MM, Liu, D, Lee, O-H, Gumin, J, Bhat, KP, Colman, H, Lang, FF, Fueyo, J, Gomez-Manzano, C
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431162/
https://ncbi.nlm.nih.gov/pubmed/19421150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.103
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