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Lack of protein kinase C-α leads to impaired urine concentrating ability and decreased aquaporin-2 in angiotensin II-induced hypertension

Regulation of water and urea transport in the inner medullary collecting duct is essential for urine concentration. Aquaporin (AQP)2 water channels and urea transporter (UT)-A1 are inserted into the apical membrane upon phosphorylation of the channels to allow the transcellular movement of water and...

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Detalhes bibliográficos
Main Authors: Thai, Tiffany L., Blount, Mitsi A., Klein, Janet D., Sands, Jeff M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431144/
https://ncbi.nlm.nih.gov/pubmed/22492943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00098.2012
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