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Fight-or-flight: murine unilateral ureteral obstruction causes extensive proximal tubular degeneration, collecting duct dilatation, and minimal fibrosis

Unilateral ureteral obstruction (UUO) is the most widely used animal model of progressive renal disease. Although renal interstitial fibrosis is commonly used as an end point, recent studies reveal that obstructive injury to the glomerulotubular junction leads to the formation of atubular glomeruli....

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Autori principali: Forbes, Michael S., Thornhill, Barbara A., Minor, Jordan J., Gordon, Katherine A., Galarreta, Carolina I., Chevalier, Robert L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431140/
https://ncbi.nlm.nih.gov/pubmed/22535799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00110.2012
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