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Fight-or-flight: murine unilateral ureteral obstruction causes extensive proximal tubular degeneration, collecting duct dilatation, and minimal fibrosis

Unilateral ureteral obstruction (UUO) is the most widely used animal model of progressive renal disease. Although renal interstitial fibrosis is commonly used as an end point, recent studies reveal that obstructive injury to the glomerulotubular junction leads to the formation of atubular glomeruli....

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Bibliographische Detailangaben
Hauptverfasser: Forbes, Michael S., Thornhill, Barbara A., Minor, Jordan J., Gordon, Katherine A., Galarreta, Carolina I., Chevalier, Robert L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431140/
https://ncbi.nlm.nih.gov/pubmed/22535799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00110.2012
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