Novikoff hepatoma deoxyribonucleic acid polymerase. Sensitivity of the beta-polymerase to sulfhydryl blocking agents.

Unlike other beta-class eukaryotic DNA polymerases, the enzyme purified from the Novikoff hepatoma is inhibited by both sulfhydryl blocking agents N-ethylmaleimide (NEM) and p-hydroxymercuribenzoate (pHMB). The degree of sensitivity varies depending on the enzyme purity, pH of the reaction, and the...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Mosbaugh, D W, Kunkel, T A, Stalker, D M, Tcheng, J E, Meyer, R R
Format: Artigo
Language:Inglês
Published: Oxford University Press 1976
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343089/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/3.9.2341
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