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The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor

The Erwinia ligand-gated ion channel (ELIC) is a bacterial homologue of vertebrate Cys-loop ligand-gated ion channels. It is activated by GABA, and this property, combined with its structural similarity to GABA(A) and other Cys-loop receptors, makes it potentially an excellent model to probe their s...

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Detalhes bibliográficos
Main Authors: Thompson, Andrew J., Alqazzaz, Mona, Ulens, Chris, Lummis, Sarah C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430861/
https://ncbi.nlm.nih.gov/pubmed/22677470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.05.027
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