Pentoxifylline decreases oxidized lipid products in nonalcoholic steatohepatitis: New evidence on the potential therapeutic mechanism

BACKGROUND: Pentoxifylline (PTX) improved histological features of nonalcoholic steatohepatitis (NASH) in a recent randomized placebo-controlled trial. However, the underlying mechanism responsible for the beneficial effects of PTX in NASH remains unidentified. A key role of lipid oxidation in the p...

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Bibliographic Details
Main Authors: Zein, Claudia O., Lopez, Rocio, Fu, Xiaoming, Kirwan, John P., Yerian, Lisa M., McCullough, Arthur J., Hazen, Stanley L., Feldstein, Ariel E.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430813/
https://ncbi.nlm.nih.gov/pubmed/22505276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25778
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