Tolerance Induction by Exosomes from Immature Dendritic Cells and Rapamycin in a Mouse Cardiac Allograft Model

BACKGROUND: Dendritic cells (DCs) release bioactive exosomes that play an important role in immune regulation. Because they express low levels of class I major histocompatibility complex (MHC) and co-stimulatory molecules, exosomes derived from donor immature DCs (imDex) prolong allograft survival b...

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Detalhes bibliográficos
Main Authors: Li, Xiao, Li, Jun-Jie, Yang, Jing-Yue, Wang, De-Sheng, Zhao, Wei, Song, Wen-Jie, Li, Wei-Min, Wang, Jian-Feng, Han, Wei, Zhang, Zhuo-Chao, Yu, Yong, Cao, Da-Yong, Dou, Ke-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430614/
https://ncbi.nlm.nih.gov/pubmed/22952868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044045
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