Identification of a novel prostate cancer susceptibility locus on chromosome 8q24

We report a genome-wide association study in 10,286 cases and 9,135 controls of European ancestry, in the Cancer Genetic Markers of Susceptibility (CGEMS) initiative, identifying a new association with prostate cancer risk on chromosome 8q24 (rs620861, p=1.3×10(-10), heterozygote OR = 1.17, 95% CI 1...

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Hoofdauteurs: Yeager, Meredith, Chatterjee, Nilanjan, Ciampa, Julia, Jacobs, Kevin B., Bosquet, Jesus Gonzalez, Hayes, Richard B., Kraft, Peter, Wacholder, Sholom, Orr, Nick, Berndt, Sonja, Yu, Kai, Hutchinson, Amy, Wang, Zhaoming, Amundadottir, Laufey, Feigelson, Heather Spencer, Thun, Michael J., Diver, W. Ryan, Albanes, Demetrius, Virtamo, Jarmo, Weinstein, Stephanie, Schumacher, Fredrick R., Cancel-Tassin, Geraldine, Cussenot, Olivier, Valeri, Antoine, Andriole, Gerald L, Crawford, E. David, Haiman, Christopher A., Henderson, Brian, Kolonel, Laurence, Le Marchand, Loic, Siddiq, Afshan, Riboli, Elio, Key, Timothy J., Kaaks, Rudolf, Isaacs, William, Isaacs, Sarah, Wiley, Kathleen E., Gronberg, Henrik, Wiklund, Fredrik, Stattin, Pär, Xu, Jianfeng, Zheng, S. Lilly, Sun, Jielin, Vatten, Lars J., Hveem, Kristian, Kumle, Merethe, Tucker, Margaret, Gerhard, Daniela S., Hoover, Robert N., Fraumeni, Joseph F., Hunter, David J., Thomas, Gilles, Chanock, Stephen J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430510/
https://ncbi.nlm.nih.gov/pubmed/19767755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.444
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