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Self-assembled supramolecular nano vesicles for safe and highly efficient gene delivery to solid tumors

The main obstacles for cationic polyplexes in gene delivery are in vivo instability and low solid-tumor accumulation. Safe vectors with high transfection efficiency and in vivo tumor accumulation are therefore highly desirable. In this study, the amphiphilic block copolymer poly(n-butyl methacrylate...

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Autors principals: Li, Wei, Li, Huafei, Li, Jinfeng, Wang, Huajing, Zhao, He, Zhang, Li, Xia, Yu, Ye, Zengwei, Gao, Jie, Dai, Jianxin, Wang, Hao, Guo, Yajun
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430442/
https://ncbi.nlm.nih.gov/pubmed/22977303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S34675
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