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Anti-NMDA Receptor Encephalitis Antibody Binding Is Dependent on Amino Acid Identity of a Small Region within the GluN1 Amino Terminal Domain

Anti-NMDA receptor (NMDAR) encephalitis is a newly identified autoimmune disorder that targets NMDARs, causing severe neurological symptoms including hallucinations, psychosis, and seizures, and may result in death (Dalmau et al., 2008). However, the exact epitope to which these antibodies bind is u...

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Главные авторы: Gleichman, Amy J., Spruce, Lynn A., Dalmau, Josep, Seeholzer, Steven H., Lynch, David R.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430387/
https://ncbi.nlm.nih.gov/pubmed/22875940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0064-12.2012
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