L-2-Oxothiazolidine-4-Carboxylic Acid or α-Lipoic Acid Attenuates Airway Remodeling: Involvement of Nuclear Factor-κB (NF-κB), Nuclear Factor Erythroid 2p45-Related Factor-2 (Nrf2), and Hypoxia-Inducible Factor (HIF)

Reactive oxygen species (ROS) play a crucial role in the pathogenesis of acute and chronic respiratory diseases. Antioxidants have been found to ameliorate airway inflammation and hyperresponsiveness in animal models employing short-term exposure to allergen. However, little data are available on th...

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Main Authors: Park, Seoung Ju, Lee, Kyung Sun, Lee, Su Jeong, Kim, So Ri, Park, Seung Yong, Jeon, Myoung Shin, Lee, Heung Bum, Lee, Yong Chul
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430212/
https://ncbi.nlm.nih.gov/pubmed/22942681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13077915
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