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Hydrolase Controls Cellular NAD, Sirtuin, and Secondary Metabolites
Cellular levels of NAD(+) and NADH are thought to be controlled by de novo and salvage mechanisms, although evidence has not yet indicated that they are regulated by NAD(+) degradation. Here we show that the conserved nudix hydrolase isozyme NdxA hydrolyzes and decreases cellular NAD(+) and NADH in...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430197/ https://ncbi.nlm.nih.gov/pubmed/22801369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00032-12 |
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