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6-Trifluoromethyl Pyridoxine: Novel (19)F-NMR pH Indicator for In Vivo Detection

pH plays an important role in tumor proliferation, angiogenesis, metabolic control and the efficacy of cytotoxic therapy, and accurate non-invasive assessment of tumor pH promises to provide insight into developmental processes and prognostic information. In this paper, we report the design, synthes...

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Detalhes bibliográficos
Main Authors: Yu, Jian-Xin, Cui, Weina, Bourke, Vincent A., Mason, Ralph P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430128/
https://ncbi.nlm.nih.gov/pubmed/22775397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm300520q
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