Stepwise proteolytic activation of type I procollagen to collagen within the secretory pathway of tendon fibroblasts in situ

Proteolytic cleavage of procollagen I to collagen I is essential for the formation of collagen fibrils in the extracellular matrix of vertebrate tissues. Procollagen is cleaved by the procollagen N- and C-proteinases, which remove the respective N- and C-propeptides from procollagen. Procollagen pro...

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Autores principales: Canty-Laird, Elizabeth G., Lu, Yinhui, Kadler, Karl E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430002/
https://ncbi.nlm.nih.gov/pubmed/21967573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111379
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