Genome-scale DNA methylation pattern profiling of human bone marrow mesenchymal stem cells in long-term culture

Human bone marrow mesenchymal stem cells (MSCs) expanded in vitro exhibit not only a tendency to lose their proliferative potential, homing ability and telomere length but also genetic or epigenetic modifications, resulting in senescence. We compared differential methylation patterns of genes and mi...

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Detalhes bibliográficos
Main Authors: Choi, Mi Ran, In, Yong-Ho, Park, Jungsun, Park, Taesung, Jung, Kyoung Hwa, Chai, Jin Choul, Chung, Mi Kyung, Lee, Young Seek, Chai, Young Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429814/
https://ncbi.nlm.nih.gov/pubmed/22684242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.8.057
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