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Minimal requirements for inhibition of MraY by lysis protein E from bacteriophage ΦX174

The DNA phage ΦX174 encodes the integral membrane protein E whose expression leads to host cell lysis by inhibition of the peptidoglycan synthesis enzyme MraY. Here we use mutagenesis to characterize the molecular details of the E lysis mechanism. We find that a minimal 18-residue region with the mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Tanaka, Shiho, Clemons, William M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429702/
https://ncbi.nlm.nih.gov/pubmed/22742425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2012.08153.x
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