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A Cremophor-Free Self-Microemulsified Delivery System for Intravenous Injection of Teniposide: Evaluation In Vitro and In Vivo

In order to tackle the problems on low water solubility of teniposide, involvement of toxic surfactant in its injection, and the poor stability during infusion, a Cremophor-free teniposide self-microemulsified drug delivery system (TEN-SMEDDS) was prepared for the first time, characterized, and eval...

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Detalhes bibliográficos
Main Authors: He, Suna, Cui, Zheng, Mei, Dong, Zhang, Hua, Wang, Xueqing, Dai, Wenbing, Zhang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429691/
https://ncbi.nlm.nih.gov/pubmed/22644709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9809-0
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