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Improvement of Dissolution and Hypoglycemic Efficacy of Glimepiride by Different Carriers

Effects of tromethamine (Tris), polyvinylpyrrolidone (PVP-K25), and low molecular weight chitosan (LM-CH) on dissolution and therapeutic efficacy of glimepiride (Gmp) were investigated using physical mixtures (PMs), coground mixtures, coprecipitates (Coppts) or kneaded mixtures (KMs), and compared w...

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Detalhes bibliográficos
Main Authors: Mohamed, Elham A., Meshali, Mahasen M., Foda, Abdel Monem M., Borg, Thanaa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429675/
https://ncbi.nlm.nih.gov/pubmed/22843078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9812-5
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