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Preparation of Irinotecan-Loaded Folate-Targeted Liposome for Tumor Targeting Delivery and Its Antitumor Activity

The purpose of this study was to investigate the in vivo distribution and antitumor activity of irinotecan (camptothecin (CPT)-11)-loaded folate-targeted liposome (F-Lip) in tumor-bearing mice following i.v. administration. Folate–poly(ethylene glycol)–distearoylphosphatidylcholine (FA–PEG–DSPE) was...

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Detalhes bibliográficos
Main Authors: Zhang, Ziqiang, Yao, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429673/
https://ncbi.nlm.nih.gov/pubmed/22639238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9776-5
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