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Novel Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Oral Delivery of Cinnarizine: Design, Optimization, and In-Vitro Assessment

Due to its extreme lipophilicity, the oral delivery of cinnarizine (CN) encounters several problems such as poor aqueous solubility and pH-dependent dissolution, which result in low and erratic bioavailability. The current study aims to design self-nanoemulsifying drug delivery systems (SNEDDS) of C...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Shahba, Ahmad Abdul-Wahhab, Mohsin, Kazi, Alanazi, Fars Kaed
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer US 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429665/
https://ncbi.nlm.nih.gov/pubmed/22760454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9821-4
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