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The Control of Skin-Permeating Rate of Bisoprolol by Ion-Pair Strategy for Long-Acting Transdermal Patches
A moderate drug permeating rate (flux) is desirable for long-acting transdermal patches. In this work, a novel simple method of controlling bisoprolol (BSP) flux by ion-pair strategy was initiated. Different ion-pair complexes including bisoprolol maleate (BSP-M), bisoprolol tartarate, bisoprolol be...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429664/ https://ncbi.nlm.nih.gov/pubmed/22639239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-012-9808-1 |
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