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Thermoresponsive nanogels for prolonged duration local anesthesia

Nanogels based on poly(N-isopropylacrylamide) are attractive vehicles for prolonged duration local anesthesia because of their tunable size, number of functional groups, thermoresponsiveness, and their anionic charge. Nerve block durations of up to nine hours were achieved using acrylic acid-loaded...

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Autors principals: Hoare, Todd, Young, Stuart, Lawlor, Michael W., Kohane, Daniel S.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429626/
https://ncbi.nlm.nih.gov/pubmed/22732383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2012.06.013
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