In vivo protein crystallization opens new routes in structural biology

Protein crystallization in cells has been observed several times in nature. However, owing to their small size these crystals have not yet been used for X-ray crystallographic analysis. We prepared nano-sized in vivo–grown crystals of Trypanosoma brucei enzymes and applied the emerging method of fre...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Koopmann, Rudolf, Cupelli, Karolina, Redecke, Lars, Nass, Karol, DePonte, Daniel P, White, Thomas A, Stellato, Francesco, Rehders, Dirk, Liang, Mengning, Andreasson, Jakob, Aquila, Andrew, Bajt, Sasa, Barthelmess, Miriam, Barty, Anton, Bogan, Michael J, Bostedt, Christoph, Boutet, Sébastien, Bozek, John D, Caleman, Carl, Coppola, Nicola, Davidsson, Jan, Doak, R Bruce, Ekeberg, Tomas, Epp, Sascha W, Erk, Benjamin, Fleckenstein, Holger, Foucar, Lutz, Graafsma, Heinz, Gumprecht, Lars, Hajdu, Janos, Hampton, Christina Y, Hartmann, Andreas, Hartmann, Robert, Hauser, Günter, Hirsemann, Helmut, Holl, Peter, Hunter, Mark S, Kassemeyer, Stephan, Kirian, Richard A, Lomb, Lukas, Maia, Filipe R N C, Kimmel, Nils, Martin, Andrew V, Messerschmidt, Marc, Reich, Christian, Rolles, Daniel, Rudek, Benedikt, Rudenko, Artem, Schlichting, Ilme, Schulz, Joachim, Seibert, M Marvin, Shoeman, Robert L, Sierra, Raymond G, Soltau, Heike, Stern, Stephan, Strüder, Lothar, Timneanu, Nicusor, Ullrich, Joachim, Wang, Xiaoyu, Weidenspointner, Georg, Weierstall, Uwe, Williams, Garth J, Wunderer, Cornelia B, Fromme, Petra, Spence, John C H, Stehle, Thilo, Chapman, Henry N, Betzel, Christian, Duszenko, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429599/
https://ncbi.nlm.nih.gov/pubmed/22286384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1859
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