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Antagonizing the innate pattern recognition receptor CD204 to improve dendritic cell-targeted cancer immunotherapy

Extensive studies have established a role of scavenger receptor CD204 in pattern recognition and ligand uptake. Strikingly, we recently revealed a previously unrecognized feature of CD204 action in attenuating T-cell activation and antitumor immunity. Blocking its activity in dendritic cells represe...

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Hlavní autoři: Yu, Xiaofei, Wang, Xiang-Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429590/
https://ncbi.nlm.nih.gov/pubmed/22934278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19728
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