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New strategies for melanoma immunotherapy: How to overcome immunosuppression in the tumor microenvironment

Using ret transgenic mouse model of spontaneous melanoma, we showed an accumulation of melanoma antigen-specific memory T cells. However, their antitumor effects could be blocked by myeloid-derived suppressor cells, tolerogenic dendritic cells and regulatory T cells. We suggest that effective melano...

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Bibliografiske detaljer
Hovedforfatter: Umansky, Viktor
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429588/
https://ncbi.nlm.nih.gov/pubmed/22934276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19713
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