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Increased Responsiveness of Peripheral Blood Mononuclear Cells to In Vitro TLR 2, 4 and 7 Ligand Stimulation in Chronic Pain Patients

Glial activation via Toll-like receptor (TLR) signaling has been shown in animals to play an important role in the initiation and establishment of chronic pain. However, our ability to assess this central immune reactivity in clinical pain populations is currently lacking. Peripheral blood mononucle...

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Detalhes bibliográficos
Main Authors: Kwok, Yuen H., Hutchinson, Mark R., Gentgall, Melanie G., Rolan, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429430/
https://ncbi.nlm.nih.gov/pubmed/22937165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044232
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