Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes

RANTES (CCL5) is a chemokine implicated in many human diseases. We previously showed that the transcription factor Kruppel-like factor 13 (KLF13) controls the late (3-5 days after activation) expression of RANTES in T lymphocytes and that KLF13 itself is translationally regulated through the 5′-untr...

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Bibliographic Details
Main Authors: Kim, Dong Seok, Zhang, Wei, Millman, Scott E., Hwang, Byung Joon, Kwon, Seok Joo, Clayberger, Carol, Pagano, Michele, Krensky, Alan M.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2012
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429307/
https://ncbi.nlm.nih.gov/pubmed/22797700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-415968
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