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Does size matter in platelet production?

Platelet (PLT) production represents the final stage of megakaryocyte (MK) development. During differentiation, bone marrow MKs extend and release long, branched proPLTs into sinusoidal blood vessels, which undergo repeated abscissions to yield circulating PLTs. Circular-prePLTs are dynamic intermed...

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Detalhes bibliográficos
Main Authors: Thon, Jonathan N., Italiano, Joseph E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429301/
https://ncbi.nlm.nih.gov/pubmed/22665937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-04-408724
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