Hypothyroidism in the Adult Rat Causes Incremental Changes in Brain-Derived Neurotrophic Factor, Neuronal and Astrocyte Apoptosis, Gliosis, and Deterioration of Postsynaptic Density

BACKGROUND: Adult hypothyroidism is a highly prevalent condition that impairs processes, such as learning and memory. Even though tetra-iodothyronine (T(4)) treatment can overcome the hypothyroidism in the majority of cases, it cannot fully recover the patient's learning capacity and memory. In...

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Bibliographische Detailangaben
Hauptverfasser: Cortés, Claudia, Eugenin, Eliseo, Aliaga, Esteban, Carreño, Leandro J., Bueno, Susan M., Gonzalez, Pablo A., Gayol, Silvina, Naranjo, David, Noches, Verónica, Marassi, Michelle P., Rosenthal, Doris, Jadue, Cindy, Ibarra, Paula, Keitel, Cecilia, Wohllk, Nelson, Court, Felipe, Kalergis, Alexis M., Riedel, Claudia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2012
Schlagworte:
Thyroid Economy: Regulation, Cell Biology, and Thyroid Hormone Metabolism and Action
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429274/
https://ncbi.nlm.nih.gov/pubmed/22870949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2010.0400
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