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A role for γS-crystallin in the organization of actin and fiber cell maturation in the mouse lens

γS-crystallin (γS) is a highly conserved component of the eye lens. To gain insights into the functional role(s) of this protein, the mouse gene (Crygs) was deleted. Although mutations in γS can cause severe cataracts, loss of function of γS in knockout (KO) mice produced no obvious lens opacity, bu...

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Detalhes bibliográficos
Main Authors: Fan, Jianguo, Dong, Lijin, Mishra, Sanghamitra, Chen, Yingwei, FitzGerald, Paul, Wistow, Graeme
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429115/
https://ncbi.nlm.nih.gov/pubmed/22715935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08669.x
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