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A role for γS-crystallin in the organization of actin and fiber cell maturation in the mouse lens

γS-crystallin (γS) is a highly conserved component of the eye lens. To gain insights into the functional role(s) of this protein, the mouse gene (Crygs) was deleted. Although mutations in γS can cause severe cataracts, loss of function of γS in knockout (KO) mice produced no obvious lens opacity, bu...

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Библиографические подробности
Главные авторы: Fan, Jianguo, Dong, Lijin, Mishra, Sanghamitra, Chen, Yingwei, FitzGerald, Paul, Wistow, Graeme
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429115/
https://ncbi.nlm.nih.gov/pubmed/22715935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08669.x
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