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Extrasynaptic Glutamate Receptor Activation as Cellular Bases for Dynamic Range Compression in Pyramidal Neurons

Repetitive synaptic stimulation overcomes the ability of astrocytic processes to clear glutamate from the extracellular space, allowing some dendritic segments to become submerged in a pool of glutamate, for a brief period of time. This dynamic arrangement activates extrasynaptic NMDA receptors loca...

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Detalhes bibliográficos
Main Authors: Oikonomou, Katerina D., Short, Shaina M., Rich, Matthew T., Antic, Srdjan D.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429100/
https://ncbi.nlm.nih.gov/pubmed/22934081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2012.00334
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