Whole-genome sequencing identifies recurrent somatic NOTCH2 mutations in splenic marginal zone lymphoma

Splenic marginal zone lymphoma (SMZL), the most common primary lymphoma of spleen, is poorly understood at the genetic level. In this study, using whole-genome DNA sequencing (WGS) and confirmation by Sanger sequencing, we observed mutations identified in several genes not previously known to be rec...

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Main Authors: Kiel, Mark J., Velusamy, Thirunavukkarasu, Betz, Bryan L., Zhao, Lili, Weigelin, Helmut G., Chiang, Mark Y., Huebner-Chan, David R., Bailey, Nathanael G., Yang, David T., Bhagat, Govind, Miranda, Roberto N., Bahler, David W., Medeiros, L. Jeffrey, Lim, Megan S., Elenitoba-Johnson, Kojo S.J.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428949/
https://ncbi.nlm.nih.gov/pubmed/22891276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120910
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