Sequence based characterization of structural variation in the mouse genome

Structural variation is widespread in mammalian genomes(1,2) and is an important cause of disease(3), but just how abundant and important structural variants (SVs) are in shaping phenotypic variation remains unclear(4,5). Without knowing how many SVs there are, and how they arise, it is difficult to...

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Main Authors: Yalcin, Binnaz, Wong, Kim, Agam, Avigail, Goodson, Martin, Keane, Thomas M., Gan, Xiangchao, Nellåker, Christoffer, Goodstadt, Leo, Nicod, Jérôme, Bhomra, Amarjit, Hernandez-Pliego, Polinka, Whitley, Helen, Cleak, James, Dutton, Rebekah, Janowitz, Deborah, Mott, Richard, Adams, David J., Flint, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428933/
https://ncbi.nlm.nih.gov/pubmed/21921916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10432
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