CCR4 blockade does not inhibit allergic airways inflammation

The CC chemokine receptor 4 (CCR4) shows selectivity for the recruitment of memory T cell subsets, including those of the T helper cell type 2 (Th2) phenotype. In humans, CCR4(+) T cells are recruited to the asthmatic lung in response to allergen challenge; however, the contribution of this pathway...

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Bibliographic Details
Main Authors: Conroy, Dolores M., Jopling, Louise A., Lloyd, Clare M., Hodge, Martin R., Andrew, David P., Williams, Timothy J., Pease, James E., Sabroe, Ian
Format: Artigo
Language:Inglês
Published: 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428841/
https://ncbi.nlm.nih.gov/pubmed/12960268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0103030
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