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Preferential protection of the minor groove of non-operator DNA by lac repressor against methylation by dimethyl sulphate.

The binding of lactose repressor to non-operator DNA was studied by the modification of several DNA's, including glycosylated DNA, with dimethyl sulphate, which affects the minor and major grooves of DNA and single stranded DNA regions. The non-specific binding of the repressor to DNA protected the...

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Udgivet i:Nucleic Acids Res
Principais autores: Kolchinsky, A M, Mirzabekov, A D, Gilbert, W, Li, L
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1976
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC342873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1250692/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/3.1.11
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