Duration and local toxicity of sciatic nerve blockade with co-injected site 1 sodium channel blockers and quaternary lidocaine derivatives

BACKGROUND AND OBJECTIVES: Quaternary lidocaine derivatives (QLDs) have recently received much attention because of their potential application in prolonged or sensory-selective local anesthesia. However, associated tissue toxicity is an impeding factor that makes QLDs unfavorable for clinical use....

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Bibliographic Details
Main Authors: Shankarappa, Sahadev A., Sagie, Itay, Tsui, Jonathan H., Chiang, Homer H., Stefanescu, Cristina, Zurakowski, David, Kohane, Daniel S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428729/
https://ncbi.nlm.nih.gov/pubmed/22914659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/AAP.0b013e31826125b3
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