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Hybridization and amplification rate correction for affymetrix SNP arrays

BACKGROUND: Copy number variation (CNV) is essential to understand the pathology of many complex diseases at the DNA level. Affymetrix SNP arrays, which are widely used for CNV studies, significantly depend on accurate copy number (CN) estimation. Nevertheless, CN estimation may be biased by several...

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Bibliografiske detaljer
Main Authors: Wang, Quan, Peng, Peichao, Qian, Minping, Wan, Lin, Deng, Minghua
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428662/
https://ncbi.nlm.nih.gov/pubmed/22691279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-5-24
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