Chromatinized Protein Kinase C-θ: Can It Escape the Clutches of NF-κB?

We recently provided the first description of a nuclear mechanism used by Protein Kinase C-theta (PKC-θ) to mediate T cell gene expression. In this mode, PKC-θ tethers to chromatin to form an active nuclear complex by interacting with proteins including RNA polymerase II, the histone kinase MSK-1, t...

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Autors principals: Sutcliffe, Elissa L., Li, Jasmine, Zafar, Anjum, Hardy, Kristine, Ghildyal, Reena, McCuaig, Robert, Norris, Nicole C., Lim, Pek Siew, Milburn, Peter J., Casarotto, Marco G., Denyer, Gareth, Rao, Sudha
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428636/
https://ncbi.nlm.nih.gov/pubmed/22969762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00260
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