Two-Component Cluster Analysis of a Large Serodiagnostic Database for Specificity of Increases of IgG Antibodies against Pertussis Toxin in Paired Serum Samples and of Absolute Values in Single Serum Samples

Measuring IgG antibodies against pertussis toxin (IgG-Ptx) with an enzyme-linked immunosorbent assay (ELISA) can be used to diagnose pertussis infection; however, the cutoff points are not unanimously defined. To determine the diagnostic specificity of increases of IgG-Ptx in paired sera and of abso...

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Main Authors: de Greeff, Sabine C., Teunis, Peter, de Melker, Hester E., Mooi, Frits R., Notermans, Daan W., Elvers, Bert, Schellekens, Joop F. P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428387/
https://ncbi.nlm.nih.gov/pubmed/22787194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00229-12
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