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Unusual five amino acid insert within subtype C HIV-1 envelope contributes to dual-tropism (X4R5)

During the course of HIV infection, some HIV-1 viruses switch from using the CCR5 (R5) coreceptor to using CXCR4 (X4). Here, we describe two subtype C isolates from a Zimbabwean patient that switched from using R5 to using both R5 and X4 with an accompanying addition of five amino acids to the V3 lo...

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Hlavní autoři: White, Elizabeth Johnston, McColgan, Bryan, Kassaye, Seble, Zijenah, Lynn, Katzenstein, David
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428204/
https://ncbi.nlm.nih.gov/pubmed/20299967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e328331f717
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