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A Systematic Review of the Pharmacokinetics of Antiepileptic Drugs in Neonates With Refractory Seizures

BACKGROUND: Neonatal seizures are associated with neurological sequelae and an increased risk of epilepsy later in life. Phenobarbital and phenytoin remain the antiepileptic drugs (AEDs) most commonly used to treat neonatal seizures, despite their suboptimal effectiveness and safety. As a result, ot...

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Detalhes bibliográficos
Main Authors: Tulloch, Joanie K., Carr, Roxane R., Ensom, Mary H.H.
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428186/
https://ncbi.nlm.nih.gov/pubmed/23118657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-17.1.31
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