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Freeform Fabricated Scaffolds with Roughened Struts that Enhance both Stem Cell Proliferation and Differentiation by Controlling Cell Shape

We demonstrate that freeform fabricated (FFF) scaffolds with a roughened surface topography can support hBMSC proliferation, while also inducing osteogenic differentiation, for maximized generation of calcified, bone-like tissue. Previously, hBMSCs rapidly proliferated, without osteogenic differenti...

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Detalhes bibliográficos
Main Authors: Kumar, Girish, Waters, Michael S., Farooque, Tanya M., Young, Marian F., Simon, Carl G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428138/
https://ncbi.nlm.nih.gov/pubmed/22417619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.02.048
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