Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections

Epidermodysplasia verruciformis (EV) is a rare genetic disorder characterized by increased susceptibility to specific human papillomaviruses, the betapapillomaviruses. These EV-HPVs cause warts and increase the risk of skin carcinomas in otherwise healthy individuals. Inactivating mutations in epide...

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Autors principals: Crequer, Amandine, Troeger, Anja, Patin, Etienne, Ma, Cindy S., Picard, Capucine, Pedergnana, Vincent, Fieschi, Claire, Lim, Annick, Abhyankar, Avinash, Gineau, Laure, Mueller-Fleckenstein, Ingrid, Schmidt, Monika, Taieb, Alain, Krueger, James, Abel, Laurent, Tangye, Stuart G., Orth, Gérard, Williams, David A., Casanova, Jean-Laurent, Jouanguy, Emmanuelle
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428089/
https://ncbi.nlm.nih.gov/pubmed/22850876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62949
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